Effect of food-satiation and food-deprivation upon the conditioned reflexes established by the Ellison-Konorski separation procedure.

Ellison anld Konorski (1964, 1965) proposed the procedure by which the separation of the instrumental motor and the cJassical salivary responses was possible within the same trial. Namely, two chained conditioned stimuli (CSs) were used; the first elicited a multiple instrumental response and the second, immediately following the first one, was merely a well established signal of food. In our previous study (1968) a solmewhat modified procedure was employed. The dogs were trained, to perform 14 lever-presses in response to a metronome, the instrumental CS (CSin), which was followed by a buzzer, the classical CS (CSC1) and fod-reinforcement. It was shown in this study that the CSi, elicited active lever-presses but also a fair rate of conditioned salivation, a result far from perfect separation betnveen motor and salivary responses such as s h m in the Ellison and Konorski studies. This discrepancy has been discussed in the previous paper (Miyata and Soltysik 1968). The primary purpose of the present investigation was to study the effect of manipulation of the hunger-drive upon CR6: established by the separation procedure described fully in our previous paper. Four tests were carried out to observe: (i) the effect of gradual satiation with food during prolonged session, (ii) the effect of acute satiation, (iii) the effect of increase of the hunger-drive, and (iv) the effect of prolongation of the CSi, under increased hunger drive.